SYNTHESIS OF THE NEW NAPROXEN SELECTIVE ELECTRODE BASED ON IMPRINTED POLYMER USING DIFFERENT MONOMERS AND ITS DETERMINATION AT PHARMACEUTICAL PREPARATION

SYNTHESIS OF THE NEW NAPROXEN SELECTIVE ELECTRODE BASED ON IMPRINTED POLYMER USING DIFFERENT MONOMERS AND ITS DETERMINATION AT PHARMACEUTICAL PREPARATION

Authors

  • Sabaa Abd Jaber
  • Yehya Kamal Al-Bayati

Keywords:

Keywords: Molecularly imprinted polymer electrodes, naproxen, potentiometric measurements, styrene(STY) monomer.

Abstract

ABSTRACT

Naproxen(NPX) imprinted liquid electrodes of polymers are built using polymerization precipitation. The molecularly imprinted (MIP) and non imprinted (NIP) polymers were synthesized using NPX as a template. In the polymerization precipitation involved, styrene(STY) was used as monomer, N,N-methylenediacrylamide (N,N-MDAM) as a cross-linker and benzoyl peroxide (BPO) as an initiator. The molecularly imprinted membranes and the non-imprinted membranes were prepared using acetophenone(AOPH) and di octylphathalate(DOP)as plasticizers in PVC matrix. The slopes and detection limits of the liquid electrodes ranged from)-18.1,-17.72 (mV/decade and )4.0 x 10-4– 5.0 x 10-4( M, respectively and their response time was about 1 minute. The electrodes of fluid are lined with 0.1(M standardsolution of drug and their response was stable in a pH range from )1.0 to 11.0( and with good selectivity for over several species. The new electrodes were successfully applied for the analyte determination in preparation pharmaceutical sample without any time consuming pretreatment steps.

Author Biographies

  • Sabaa Abd Jaber

    1Department of Chemistry, College of Science, University of Baghdad, Iraq [email protected].

  • Yehya Kamal Al-Bayati

    2Prof. Dr. Department of Chemistry, College of Science, University of Baghdad, Iraq yahyaalbayti@yahoo

Published

2020-12-31

How to Cite

SYNTHESIS OF THE NEW NAPROXEN SELECTIVE ELECTRODE BASED ON IMPRINTED POLYMER USING DIFFERENT MONOMERS AND ITS DETERMINATION AT PHARMACEUTICAL PREPARATION: SYNTHESIS OF THE NEW NAPROXEN SELECTIVE ELECTRODE BASED ON IMPRINTED POLYMER USING DIFFERENT MONOMERS AND ITS DETERMINATION AT PHARMACEUTICAL PREPARATION. (2020). Iraqi Journal of Market Research and Consumer Protection, 12(2), 1-11. https://jmracpc.uobaghdad.edu.iq/index.php/IJMRCP/article/view/203