STUDY OF SOME IMMUNOLOGICAL PARAMETERS IN PATIENT THAT INFUCTED WITH Streptococcus pyogenes

Abstract

A streptococci has recognized as Streptococcus spp., associate with acute pharyngitis. S. pyogenes infection Has detected in the Hospital and Health Center in Tikrit city. Throat swabs sample has obtained and cultured on a sheep blood agar plate. Identification of S. pyogenes was performed by using the VITEK 2 automatic system. It detected of 50 samples from children included 25 were positive for S. pyogenes infection. were aged 10-35 years old and included 30 male and 20 female. . While 25 sample Negative of S. pyogenes infection (The control group included 25 clinically healthy children without S. pyogenes infection matched for age and sex with cases pateints). No significant differences was reported between tonsillitis patients and healthy control in terms of Complement 4 proteins (33.21 ±14.18726 , 35.57±15.56254) , C3 (268.5±14.34 , 146.06±17.83) although increased complement level in patient group. The present study revealed no significant decrease levels of C4 of tonsillitis patients with negative ASOT than those with positive. the disease duration and ASOT have significant effect on CRP and complements components serum levels in patients with tonsillitis.