IN VITRO EVALUATION OF THE EFFECT OF A BOTANICAL COMBINATION ON CANCER CELL CONTROL

Abstract

The present century has witnessed the development of green synthesis of silver nanoparticles (AgNPs) and its wide application in the medical field. The green synthesis method is the most stable, highly effective and easy to prepare method for producing AgNPs. Figs, olives and moringa trees are grown in Iraq and have been mentioned in the Holy Qur’an several times and their benefits, as well as the proof of intensive scientific studies of the benefits of figs, olives and moringa, whether their leaves or fruits against microbes, oxidation, cancer and various therapeutic applications. Accordingly, the study aimed to examine the plant composition of leaves (fig, olive and moringa) and the possibility of forming AgNPs nanoparticles against the activity of cancer cells. The surface properties of AgNPs were confirmed and described by UV-Vis, XRD, SEM, TEM, AFM and FTIR spectrophotometry. And also FESEM, TEM technique was used to find the average size and the morphological shape of AgNPs. And the TEM results showed the average size of the nanoparticles of the plant synthesis of fig, olive and moringa (FOM) between 44.08-71.57 nm. Also, the ability of FOM mixture extract with silver nanoparticles to inhibit a type of FCM 7 cancer cell lines was studied. The results of the study showed the significant presence of the biological active components of the plant synthesis. Also, the ability of FOM mixture extract with silver nanoparticles to inhibit a type of FCM 7 cancer cell lines was studied. The results of the study showed the significant presence of the biological active components of the plant synthesis. Nanomaterials of synthetic nanoparticles have also demonstrated the size and shape of the nanoparticles and the presence of reactive chemical bonding sites. The study also proved that using concentrations higher than 50 µg/mL that there is a possibility to kill and inhibit the growth of cancer cells of type FCM 7 in later study.