RATE CONSTANT OF SOME AMINO DERIVATIVES DISSOCIATION

RATE CONSTANT OF SOME AMINO DERIVATIVES DISSOCIATION

  • Anud M. A. Efhema
  • Ziadan J. Khalaf
Keywords: Keywords: Amino glycosides, derivative reagents, conduct metric measurement, dissociation constant calculation.

Abstract

Amino glycoside derivation including, Neomycin, Streptomycin, Kanamycin and Gentamycin with special reagents, which  are  benzoylchloride; benzene sulfonyl chloride and phthalic anhydride were made to enhance Uv-detectability for HPLC analysis. But there are many problems facing pre column derivation and in order to solve this, the conductivity of antibiotic derivatives were used to calculate the dissociation constant and the hydrolysis rate which determined concern type reaction. In addition the  characteristics those controlling the hydrolysis of antibiotic-derivatives were investigated.

Author Biographies

Anud M. A. Efhema

1Department of Chemistry, Faculty of Science, Sirte University, Sirte, Libya. [email protected]

Ziadan J. Khalaf

2Department of Chemistry, Faculty of Science, Sirte University, Sirte, Libya. [email protected]

Published
2021-06-30
How to Cite
Efhema, A., & Khalaf, Z. (2021). RATE CONSTANT OF SOME AMINO DERIVATIVES DISSOCIATION. Iraqi Journal of Market Research and Consumer Protection, 13(1), 148-166. Retrieved from https://jmracpc.uobaghdad.edu.iq/index.php/IJMRCP/article/view/238