ASSOCIATION OF CYP17 GENE POLYMORPHISME IN PRODUCTIVE AND REPRODUCTIVE PERFORMANCE IN GOAT

Abstract

This study was conducted in the Ruminants Research Station, Office of Agricultural Research/ Ministry of Agriculture- Iraq to detect CYP17 gene polymorphisms in Local and Shami goat, as well as to establish if SNPs could be associated with some productive and reproductive traits such as total milk yield (TMY) and its components, in addition to reproductive traits which included litter size and fertility. An important single nucleotide polymorphisms (SNPs) (G2276C) were found in the studying fragment (804 bp), which include  Exon2, intron2, and partial of Exon3 by using DNA sequencing technique, two genotypes were produced wild GG and GC in both breeds. Results proposed a highly differences among distribution of genotypes percentage and allele frequencies in both breeds, Results stated a significant relationship between polymorphisms of this SNPs and milk fat percentage and litter size, where hetero genotype GC exceeded GG genotype in milk fat percentage and litter size in Local goat, whereas wild genotype GG distinguished in milk fat percentage in Shami goat.