ISOLATION AND IDENTIFICATION OF ORAL BACTERIA FROM IRAQI PATIENTS WITH ORAL INFECTION AND DETERMINING THE RESISTANCE OF PATHOGENIC ISOLATES TO ANTIBIOTIC

Abstract

A complex and diversified microbial community vital to both health and disease is found in the mouth cavity. Periodontal disease, dental cavities, and severe oral infections. The variety of oral microbiota, which includes certain opportunistic, potentially harmful bacterial and fungal strains that were found in comparatively high prevalence among the individuals under analysis, may raise the possibility of infections spreading from the mouth to nearby tissues and other organs. The main roles that oral pathogenic bacteria can play in infection are outlined in current research. A total of 100 oral swabs clinical samples were specifically obtained from 100 patients, both male and female, aged 2 to 70 years, who had various types of oral infections. Of these, 40 samples from healthy individuals were selected as control samples, 60 samples were patients with oral infection (dental caries, Periodontal disease and tooth decay) without taking any treatment at the time the samples were being collected. Using the Vitek-2 technique, the distribution of harmful bacteria among the presumed isolates revealed that 82,3% of the isolates were pathogenic and 17,6% were normal flora. Antibiotic susceptibility tests utilizing the Vitek-2 method have produced the following results. All isolate were 50% resistant to Amoxicillin, Gentamicin, Cephalothin, Tetracycline, Ceftriaxone, Amoxicillin, Erythromycin, Cefixime, Ciprofloxacin, Azithromycin. Isolates exhibit remarkable sensitivity to numerous antibiotics, such as (Clarithromycin, Cephalothin, Cefixime, and Ciprofloxacin. The results of this retrospective investigation showed how urgently pretreatment assessment of oral microbiota components has to be prioritized. Particularly those strains that are very harmful to senior citizens and are recognized as human opportunistic infection etiological agents.