Iraqi Pharmaceutical Formula for Clonazepam Oral Drop 2.5 mg/ ml to Treat Seizure Epilepsy in Infants and Children with its Stability Study.

Iraqi Pharmaceutical Formula for Clonazepam Oral Drop 2.5 mg/ ml to Treat Seizure Epilepsy in Infants and Children with its Stability Study.

Authors

  • Qusae faddel abas
  • zina medhat ebrahim
  • hadil harith khalid
  • amer khazal sahi

Keywords:

Clonazepam, Oral Drop, Seizure Epilepsy.

Abstract

This work has been carried out to develop national drug product contains 2.5mg/ml clonazepam as oral drop; it is used for the treatment of epilepsy in infants and children.
Several formulations were prepared using oral drop base, flavor, buffer, sweeteners and preservatives. Selection of best formula relied solely on physic-chemical testing of samples.
Stability study was conducted on the product for six months at different temperatures to determine the expiration date and the best storage conditions.
From the study we obtained an oral drop of good clear solution. The expiry date calculated to be not less than 2 years.

Author Biographies

  • Qusae faddel abas

    Minisitry of Industry, Minerals opration for Research and Industrial Development IBN SINA

  • zina medhat ebrahim

    Minisitry of Industry, Minerals opration for Research and Industrial Development IBN SINA

  • hadil harith khalid

    Minisitry of Industry, Minerals opration for Research and Industrial Development IBN SINA

  • amer khazal sahi

    Minisitry of Industry, Minerals opration for Research and Industrial Development IBN SINA

Published

2016-05-23

How to Cite

Iraqi Pharmaceutical Formula for Clonazepam Oral Drop 2.5 mg/ ml to Treat Seizure Epilepsy in Infants and Children with its Stability Study.: Iraqi Pharmaceutical Formula for Clonazepam Oral Drop 2.5 mg/ ml to Treat Seizure Epilepsy in Infants and Children with its Stability Study. (2016). Iraqi Journal of Market Research and Consumer Protection, 8(1), 386-394. https://jmracpc.uobaghdad.edu.iq/index.php/IJMRCP/article/view/79