SYNTHESIS, CHARACTERIZATION AND STUDY THE BIOLOGICAL ACTIVITIES OF NEW HETEOCYCLIC COMPOUNDS CONTAINIG CREATININE

SYNTHESIS, CHARACTERIZATION AND STUDY THE BIOLOGICAL ACTIVITIES OF NEW HETEOCYCLIC COMPOUNDS CONTAINIG CREATININE

Authors

  • Rana Abid Ali
  • Entesar O. Al-Tamimi
  • Shatha Abdul Wadood

DOI:

https://doi.org/10.28936/10.28936/(1)jmracpc11.2.2019

Keywords:

Schiff bases, imidazolidine-4-one, thiazolidine-4-one, oxazolidine-4-one, anti-microbial activity

Abstract

This work included the synthesis of new heterocyclic compounds containing creatinine moiety (A4-A9). These compounds were synthesized from reaction of Schiff bases (A2, A3) with glycine, thioglycolic acid, and glycolic acid to produce imidazolidine-4-one (A4, A5), thiazolidine-4-one A6, A7, and oxazolidine-4-one (A8, A9) respectively. FTIR and 1HNMR were used to identify these compounds. In vitro experiments, the antimicrobial properties of compounds (A1, A2, and A4) were evaluated and showed good results.

Author Biographies

  • Rana Abid Ali

    1Assistant Professor PhD. Dept. of Chemistry, College of Sciences, University. of Baghdad, Baghdad, Iraq [email protected]

  • Entesar O. Al-Tamimi

    2 Professor PhD. Dept. of Chemistry, College of Sciences, University of Baghdad, Baghdad, Iraq [email protected]                    

  • Shatha Abdul Wadood

    3 Professor PhD. Dept. of Chemistry, College of Sciences, University of Baghdad, Baghdad, Iraq [email protected]

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Published

2024-06-30

Issue

Vol. 16 No. (1) (2024): Iraqi Journal of Market Research and Consumer Protection

Section

Articles

License

Copyright (c) 2024 Iraqi Journal of Market Research and Consumer Protection

Creative Commons License

This work is licensed under a Creative Commons Attribution 4.0 International License.

How to Cite

SYNTHESIS, CHARACTERIZATION AND STUDY THE BIOLOGICAL ACTIVITIES OF NEW HETEOCYCLIC COMPOUNDS CONTAINIG CREATININE: SYNTHESIS, CHARACTERIZATION AND STUDY THE BIOLOGICAL ACTIVITIES OF NEW HETEOCYCLIC COMPOUNDS CONTAINIG CREATININE. (2024). Iraqi Journal of Market Research and Consumer Protection, 16((1), 146-154. https://doi.org/10.28936/10.28936/(1)jmracpc11.2.2019